Activation of hematoporphyrin in alternating magnetic field: possible implications for cancer treatment.

نویسندگان

  • M Babincová
  • P Sourivong
  • D Leszczynska
  • P Babinec
چکیده

A new mechanism of cell damage by alternating magnetic field with hematoporphyrin is described. C6 glioblastoma cell suspensions were exposed to an alternating magnetic field with frequency 180 kHz up to 60 min in the presence of hematoporphyrin in H2O and in D2O. The results presented suggest that an alternating magnetic field is able to activate hematoporphyrin, and this method may be a basis for cancer treatment.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Induced tissue cell death by magnetic nanoparticle hyperthermia for cancer treatment: an in silico study

In this paper, we simulate magnetic hyperthermia process on a mathematical phantom model representing cancer tumor and its surrounding healthy tissues. The temperature distribution throughout the phantom model is obtained by solving the bio-heat equations and the consequent cell death amount is calculated using correlations between the tissue local temperature and the cell death rate. To have a...

متن کامل

Evaluation of a Novel Thermobrachytherapy Seed for Concurrent Administration of Brachytherapy and Magnetically Mediated Hyperthermia in Treatment of Solid Tumors

Concurrent hyperthermia and radiation therapy in treatment of cancer show a strong evidence of a synergistic enhancement. We designed a new self-regulating Thermo-Brachytherapy seed, which serves as a source of both radiation and heat for concurrent administration of brachytherapy and hyperthermia. The Thermo-Brachytherapy seed has a core of ferromagnetic material which produces heat when subje...

متن کامل

Micromachining the Aluminium Tubes Using Abrasive Finishing in Alternating Magnetic Field

This study introduced a method based on magnetic field assisted finishing mechanism for micromachining the inner surfaces of Aluminum tubes. In this approach, using the alternating magnetic field of an AC electromotor, abrasive particles were formed as Magnetic Rods (Magnetic Clusters) and surface micromachining was carried out by the dynamic particular pattern made by an alternating magnetic f...

متن کامل

Photodynamic Therapy: A New Approach to Remove Embryos of the Wistar Rat

Background Photodynamic therapy (PDT) is a promising new cancer treatment strategy which inactivates tumor cells by simultaneoulsy using light and a photosensitizer. The similarity between tumors and newly implanted embryos is notable. Extrauterine pregnancy (EUP) does not have a definite treatment and previous therapeutic options (medical and surgical) have not been effective or suitable. Ther...

متن کامل

New Achievements in Fe3O4 Nanofluid Fully Developed Forced Convection Heat Transfer under the Effect of a Magnetic Field: An Experimental Study

Fe3O4 nanofluid fully developed forced convection inside a copper tube is empirically investigated under the effect of a magnetic field. All of the investigations are performed under laminar flow regime (670≤Re≤1700) and thermal boundary conditions of the tube with uniform thermal flux. The tube is under the effect of a magnetic field in certain points. This research aims to study the effect of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 54 11  شماره 

صفحات  -

تاریخ انتشار 1999